Prof Peter Howarth
BSc (Hons), MBBS, DM, FRCP, FFPM (Hon)
Professor Emeritus of Allergy and Respiratory Medicine, University of Southampton; Global Clinical Scientific Lead GSK
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Professor Peter Howarth is Global Clinical Scientific Lead at GSK and Professor Emeritus of Allergy and Respiratory Medicine at the University of Southampton, where he still has on-going research interactions related to severe asthma.
Professor Howarth has published over 350 peer-reviewed papers, with an H-index of 104 and has contributed to National, European and International (World Health Organisation) guidelines on the management of rhinitis and asthma. He has been involved in EU funded collaborative programmes, such as ENFUMOSA, BIOAIR and U-BIOPRED, focusing on severe asthma and GA2LEN dealing with allergic disease.
Landmark publications:
Bousquet J, Van Cauwenberge P, Khaltaev N; Aria Workshop Group; World Health Organization. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol. 2001 Nov;108(5 Suppl):S147-334.
Pavord ID, Korn S, Howarth P, Bleecker ER, Buhl R, Keene ON, Ortega H, Chanez P. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet. 2012 Aug 18;380(9842):651-9.
Grainge CL, Lau LC, Ward JA, Dulay V, Lahiff G, Wilson S, Holgate S, Davies DE, Howarth PH. Effect of bronchoconstriction on airway remodelling in asthma. N Engl J Med. 2011 May 26;364(21):2006-15.
Woodcock A, Forster L, Matthews E, Martin J, Letley L, Vickers M, Britton J, Strachan D, Howarth P, Altmann D, Frost C, Custovic A; Medical Research Council General Practice Research Framework. Control of exposure to mite allergen and allergen-impermeable bed covers for adults with asthma. N Engl J Med. 2003 Jul 17;349(3):225-36.
Djukanović R, Wilson JW, Britten KM, Wilson SJ, Walls AF, Roche WR, Howarth PH, Holgate ST. Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma. Am Rev Respir Dis. 1992 Mar;145(3):669-74.
Green BJ, Wiriyachaiporn S, Grainge C, Rogers GB, Kehagia V, Lau L, Carroll MP, Bruce KD, Howarth PH. Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma. PLoS One. 2014 Jun 23;9(6):e100645.
Pilette C, Canonica GW, Chaudhuri R, Chupp G, Lee FE, Lee JK, Almonacid C, Welte T, Alfonso-Cristancho R, Jakes RW, Maxwell A, Price RG, Howarth P. REALITI-A Study: Real-World Oral Corticosteroid-Sparing Effect of Mepolizumab in Severe Asthma. J Allergy Clin Immunol Pract. 2022 Oct;10(10):2646-2656.