Respiratory and Allergy:
Earlier diagnosis and personalised treatment
Leads: Prof Jane Lucas, Dr Ramesh Kurukulaaratchy
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We are investigating how to improve clinical outcomes for respiratory diseases and allergies, through earlier diagnosis and personalised treatment.



Health needs we are tackling
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How can we improve clinical outcomes through earlier diagnosis and personalised treatment?
We are developing new diagnostic and precision medicine tools for identifying disease earlier and targeting treatments:
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Improving diagnosis: we are identifying new markers of early respiratory disease to improve diagnosis.
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Precision-medicine treatments: we are developing ways to predict how patients with lung diseases or allergy will respond to medicines.
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Treating multiple conditions: we are targeting treatment to those with multiple conditions to improve outcomes, for example by investigating the best treatment for someone with anxiety, obesity and severe asthma.
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We are also developing new strategies to predict, avoid and pre-emptively treat acute exacerbations (worsening of symptoms):
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Predicting exacerbations: we are using new digital technologies to predict exacerbations.
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Targeted treatment: we are developing patient-centred, rapid, targeted treatments for acute exacerbations – for example by using point-of-care tests to quickly find out what sub-type of a disease someone has.

