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Prof Ying Cheong


Professor of Reproductive Medicine
Honorary Consultant, University Hospital Southampton NHS FT
Medical Director, Complete Fertility Southampton
Visiting Professor, University of Malaya, Malaysia

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Ying is a Subspecialist in Reproductive Medicine and Surgery and the Professor of Reproductive Medicine. 

She is the Medical Director of Complete Fertility Centre Southampton, UK. Ying’s research is on the endometrium and its environment for implantation and works across discipline with the School of Electronics and Computer Science and Nanoscience, University of Southampton in the development of nano-therapeutics and medical biosensors. She holds several NIHR and commercial grants and is an experience clinical trialist. 

She is currently an editor within the Cochrane Gynaecology and Fertility group, and Scientific Report, a journal from Nature’s publishing group. Ying is active in undergraduate and postgraduate teaching.

Landmark publications: 

Mifepristone and misoprostol versus misoprostol alone for the management of missed miscarriage (MifeMiso): a randomised, double-blind, placebo-controlled trial

Justin Chu, Adam Devall, Leanne Beeson, Pollyanna Hardy, Versha Cheed, Yongzhong Sun, Tracy Roberts, C. Okeke Ogwulu, Eleanor Williams, Laura Jones, Jenny La Fontaine

Development, implementation and initial feasibility testing of the MediEmo mobile application to provide support during medically assisted reproduction

Isla F Robertson, China Harrison, Ka Ying Bonnie Ng, Nick Macklon, Ying Cheong, & Jacky Boivin , 2022 , Human Reproduction , 37 (5) , 1007

Papadopoulos, Ruth Bender-Atik, Jane Brewin, Kim Hinshaw, Meenakshi Choudhary, Amna Ahmed, Joel Naftalin, Natalie Nunes, Abigail Oliver, Feras Izzat, Kalsang Bhatia, Ismail Hassan, Yadava Jeve, Judith Hamilton, Shilpa Deb, Cecilia Bottomley, Jackie Ross , Linda Watkins, Martyn Underwood, Ying Cheong, Chitra Kumar, Pratima Gupta, Rachel Small, Stewart Pringle, Frances Hodge, Anupama Shahid, Ioannis Gallos, Andrew Horne, Siobhan Quenby, & Arri Coomarasamy , 2020 , The Lancet , 396 (10253) , 770—778

In-vivo oxygen, temperature and pH dynamics in the reproductive tract and their importance in human conception

Ka Ying Bonnie Ng, Roel Mingels, Hywel Morgan, Nick Macklon, & Ying Cheong , 2018 , Human Reproduction Update , 24 (1) , 15—34

A randomized trial of progesterone in women with recurrent miscarriages

A. Coomarasamy, H. Williams, E. Truchanowicz, P.T. Seed, R. Small, S. Quenby, P. Gupta, F. Dawood, Y.E.M. Koot, R. Bender Atik, K.W.M. Bloemenkamp, R. Brady, A.L. Briley, R. Cavallaro, Y.C. Cheong, J.J. Chu, A. Eapen, A. Ewies, A. Hoek, E.M. Kaaijk, C.A.M. Koks, T.-C. Li, M. MacLean, B.W. Mol, J. Moore, J.A. Ross, L. Sharpe, J. Stewart, N. Vaithilingam, R.G. Farquharson, M.D. Kilby, Y. Khalaf, M. Goddijn, L. Regan, & R. Rai , 2015 , New England Journal of Medicine , 373 (22) , 2141--2148

DOI: 10.1056/NEJMoa1504927

Major grants: 

2020-2024   STOP-OHSS (Shaping and Trialling Outpatient Protocols for Ovarian   Hyper-Stimulation Syndrome): A feasibility study and randomised controlled   trial, with internal pilot, to assess the clinical and costeffectiveness of   earlier active management of OHSS. (Health Technology Assessment (HTA).   Metwally M, Drakeley A, Cheong Y (PI), Balen A, White D, Dimairo M…Pye   C.

2020-2024   HELP Infertility (Hysteroscopic Excision of Leiomyoma and Polyp in   Infertility): two randomised controlled trialsNational Institute for Health   Research (Health Technology Assessment (HTA). Metwally, M, Latimer N, Jackson   H, Scaife C, White D, Walters S, Pye C, El-Toukhy T, Choudhary M, Mostafa H,   Gelbaya T, Lavery S, Mathur R, Saridogan E…CheongY (PI), Balan A, Child T.

Functional   gene mapping of the endometrial phenotype involved in successful and   unsuccessful pregnancy: combining 3D imaging and single cell transcriptomics.   Wellbeing of Women

2018-2021   Cheong (PI). Letrozole or Clomifene, with or without metformin, for ovulation   induction in women with polycystic ovary syndrome: a 2x2 factorial design   randomised trial (The LOCI trial)

2018-2022   Cheong YC (CI) Intra-Uterine SENSing using a batteryless, wireless   intrauterinE platform (U-SENSE). National Institute for Health Research   Invention for Innovation (i4i).

Impact example: 

Versobiosense is a spin out company from University of Southampton, founded by Prof Cheong and her colleagues, now located in Oxford Business Park. It employs over 30 personnel and has transitioned into a commercial entity. The company focuses on biosensors of in vivo environment.

Complete Fertility was founded by Prof Cheong and her colleagues. In 2018, it was privatised by the NHS and is now owned by Virtus health; the centre now employs over 50 staff, is active in research and training and importantly, treats thousands of NHS and private patients with infertility every year.

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