Dr Thomas Daniels
MBBS, BSc (hons), DM, FRCP
Consultant Respiratory Physician
Profile page(s)
Dr Daniels has been a respiratory and Cystic Fibrosis (CF) consultant physician at University Hospital Southampton since 2009.
He is involved in many different areas of research including molecular microbiology and clinical aspects of CF care. More recently he has extended his research into applications of Machine Learning into clinical care, in CF, Emergency Department care, and in Early Warning Scores.
Landmark publications:
Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium. Bryant JM, Grogono DM, ........Daniels T.......... Parkhill J, Floto RA. Science. 2016 Nov 11;354(6313):751-757
Using explainable machine learning to characterise data drift and detect emergent health risks for emergency department admissions during COVID-19. Duckworth, C., Chmiel, F.P., Burns, D.K., Zlatev, Z.D., White, N.M., Daniels, T.W., Kiuber, M. and Boniface, M.J., 2021.. Scientific reports, 11(1), pp.1-10
Nasal irrigation and gargling with hypertonic saline to prevent transmission of SARS-CoV-2 to care home residents – a feasibility cluster trial. Buchanan RM, Ibrahim K, Roberts HC, Stuart B, Webley F, Eminton Z, Ball B, Chinnery F, Parkes J, Wyatt J, Daniels T. J Nursing Home Res 2021;7:13-16
Daniels TWV, Rogers GB, Stressman, FA, van der Gaast CJ, Bruce KD, Jones GR, Connett GJ, Legg JP, and Carroll MP. Impact of antibiotic treatment for pulmonary exacerbations on bacterial diversity in cystic fibrosis. Journal of Cystic Fibrosis 2013; 12: 22-28.
Major grants:
2022: EXACT CF ExACT-CF: Exercise as an Airway Clearance Technique in people with Cystic Fibrosis – A randomised pilot trial; NIHR RfPB; collaborator, advisor and coordination role, and local PI; amount £235,070.
2020: Harnessing the Potential of Machine Learning to improve Patient Safety and Staff Efficiency; Dinwoodie Charitable Trust, I am CI, £145,378, ongoing. This includes 18 months of 2 PAs of funding for my time (ends end of April 2022), data extraction costs and UoC analytics costs.
2019: CF Trust Venture and Innovation Award; “Non-tuberculosis mycobacteria infection and the wider lung microbiota in cystic fibrosis” funded by Cystic Fibrosis Trust; main applicant is Professor C van der Gaast at Manchester Metropolitan University and I am lead clinician and co-investigator; amount £96,000; ongoing.