Professor Sarah Ennis is Professor of Genomics within Medicine at the University of Southampton.

Sarah Ennis holds a first class honours degree in Biochemistry from National University Ireland (Galway) and a PhD in Genetic Epidemiology (University of Southampton). Her career has evolved with the emerging field of Human Genomics and she now leads the Human Genetics & Genomic Medicine Research theme and her own research group in Genomic Informatics. Her group specialises in the analysis of next generation sequencing (NGS) data and these are focussed on, but not limited to: interrogation of targeted and whole genome sequence data to determine cryptic causes of Mendelian disease; large scale genomic data analysis, including data integration and machine learning to better understand the genetic basis of rare and common disease with the aim of stratifying diagnoses and targeting tailored treatment for better patient outcomes; the application of whole genome sequence data for the generation of optimally resolved genetic maps and the correlation of these maps with genetic motifs, recombination and selection.

SE holds an honorary NHS contract, works closely with clinical colleagues across various NHS Trusts. She is Chief Investigator of NIHR portfolio research recruiting thousands of patients and families into clinical research. SE is a Research Director within the Central and South Genomic Medicine Service Alliance - a national network of seven such alliances represent the strategic bodies that oversees the establishment of genomic testing pathways throughout the NHS service as well as the operational and digital functions to enable optimal utility of genomic data for better patient outcomes.

Prof. Ennis’ group comprises senior postdoctoral researchers, clinical research staff and senior research nurses. She supervises a diverse group of MSc and PhD students as well as undergraduate student projects. She lectures in Biochemistry, Molecular Cell Biology and Genomics within the BM5 Medical Degree Programme and Module Lead within the MSc in Genomic Medicine.